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Immunological Bioinformatics: Predicting MHC Class II Epitopes

Hossam Elsemellawy, Amr Badr, Mostafa Abdelazim

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 |  2015-10-08 |  2015-10-08 | Original language:English | PDF # 1 |  8.66 x.24 x5.91l,.36 | File type: PDF | 104 pages

||About the Author|Hossam Elsemellawy is Researcher in the Arab Academy for Science, Technology and Maritime Transport, Egypt. Amr Badr is a Prof. of Computer Science, Cairo University, Egypt. Mostafa Abdelazim is a Prof. of Computer Science in the Arab Academy fo

Successful Prediction for Major Histocompatibility Complex (MHC) molecule epitopes is an essential step in designing Genetic Vaccines. Successful prediction of MHC class II epitopes is more difficult than MHC class I epitopes due to open binding groove at both ends in class II molecules, this structure leads to variable length for MHC II epitopes and complicating the task for detecting the core binding 9-mer. In this Book we presented a novel classification algorithm for...

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