[PDF.29ho] DNA Topoisomerase Protocols, Part 1: DNA Topology and Enzymes (Methods in Molecular Biology, Vol. 94)

DNA Topoisomerase Protocols, Part 1: DNA Topology and Enzymes (Methods in Molecular Biology, Vol. 94)

[PDF.gz33] DNA Topoisomerase Protocols, Part 1: DNA Topology and Enzymes (Methods in Molecular Biology, Vol. 94)

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 | #5511754 in Books |  Humana Press |  1999-03-23 | Original language:English | PDF # 1 |  9.21 x.81 x6.14l,1.42 | File type: PDF | 327 pages

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|| |"...an invaluable practical aid. The central and expanding role of these enzymes in basic cell biology together with their important pharmaceutical applications will ensure that book will remain relevant for some years to come."-Cell Biology International 200

Beginning with the Escherichia coli co protein, or bacterial DNA topoisomerase I, an ever-increasing number of enzymes has been identified that catalyze changes in the linkage of DNA strands. DNA topoisomerases are ubiquitous in nature and have been shown to play critical roles in most p- cesses involving DNA, including DNA replication, transcription, and rec- bination. These enzymes further constitute the cellular targets of a number of clinically important antibacteria...

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